Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | XBP1 | P17861 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4701925 | 0.81 | ALDH1A1 (0.67) | ALDH1A1CYP2C19MEN1KMT2AMAPT | |
| SCHEMBL4701930 | 0.81 | ALDH1A1 (0.67) | ALDH1A1CYP2C19MEN1KMT2AMAPT | |
| SCHEMBL31694172 | 0.78 | ALDH1A1 (0.70) | ALDH1A1CYP2C19MEN1KMT2AMAPT | |
| SCHEMBL12000583 | 0.78 | ALDH1A1 (0.70) | ALDH1A1CYP2C19MEN1KMT2AMAPT | |
| SCHEMBL7015328 | 0.77 | ALDH1A1 (0.61) | ALDH1A1CYP2C19MEN1KMT2AMAPT | |
| SCHEMBL7015325 | 0.77 | ALDH1A1 (0.61) | ALDH1A1CYP2C19MEN1KMT2AMAPT | |
| SCHEMBL7020831 | 0.74 | ALDH1A1 (0.70) | ALDH1A1CYP2C19MEN1KMT2AMAPT | |
| SCHEMBL7020834 | 0.74 | ALDH1A1 (0.70) | ALDH1A1CYP2C19MEN1KMT2AMAPT | |
| SCHEMBL7018307 | 0.74 | ALDH1A1 (0.70) | ALDH1A1CYP2C19MEN1KMT2AMAPT | |
| SCHEMBL7018314 | 0.74 | ALDH1A1 (0.70) | ALDH1A1CYP2C19MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2650284-A1 | Heterocyclic derivatives as metabotropic glutamate receptor modulators | Merz Pharma GmbH & Co. KGaA (DE) | 2013-10-16 | — | — | EP | disclosed |