Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.84 |
| ▸ | THRB | P10828 | 10/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.84 |
| ▸ | BLM | P54132 | 9/20 | 0.84 |
| ▸ | RECQL | P46063 | 8/20 | 0.84 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.84 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.84 |
| ▸ | MAPT | P10636 | 7/20 | 0.84 |
| ▸ | BRCA1 | P38398 | 7/20 | 0.84 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.84 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.84 |
| ▸ | TOP2A | P11388 | 5/20 | 0.84 |
| ▸ | HTT | P42858 | 5/20 | 0.84 |
| ▸ | STAT6 | P42226 | 5/20 | 0.84 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.84 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.84 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.84 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607868 | 1.00 | MEN1 (0.84) | MEN1THRBKMT2ABLMRECQL | |
| SCHEMBL10119585 | 1.00 | MEN1 (0.84) | MEN1THRBKMT2ABLMRECQL | |
| SCHEMBL15890537 | 1.00 | MEN1 (0.84) | MEN1THRBKMT2ABLMRECQL | |
| SCHEMBL94868 | 1.00 | MEN1 (0.84) | MEN1THRBKMT2ABLMRECQL | |
| SCHEMBL10061864 | 1.00 | MEN1 (0.84) | MEN1THRBKMT2ABLMRECQL | |
| SCHEMBL17752025 | 1.00 | MEN1 (0.84) | MEN1THRBKMT2ABLMRECQL | |
| SCHEMBL9889375 | 1.00 | MEN1 (0.84) | MEN1THRBKMT2ABLMRECQL | |
| SCHEMBL9889374 | 1.00 | MEN1 (0.84) | MEN1THRBKMT2ABLMRECQL | |
| SCHEMBL9942593 | 1.00 | MEN1 (0.84) | MEN1THRBKMT2ABLMRECQL | |
| SCHEMBL9607869 | 1.00 | MEN1 (0.84) | MEN1THRBKMT2ABLMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230364247-A1 | NON-LINEAR MULTIBLOCK COPOLYMER-DRUG CONJUGATES FOR THE DELIVERY OF ACTIVE AGENTS | THE JOHNS HOPKINS UNIVERSITY | 2023-11-16 | — | — | US | disclosed |
| US-11660349-B2 | Non-linear multiblock copolymer-drug conjugates for the delivery of active agents | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-05-30 | — | — | US | disclosed |
| US-9950072-B2 | Controlled release formulations for the delivery of HIF-1 inhibitors | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-04-24 | — | — | US | disclosed |
| US-20150141359-A1 | Controlled Release Formulations for the Delivery of HIF-1 Inhibitors | THE JOHNS HOPKINS UNIVERSITY | 2015-05-21 | — | — | US | disclosed |
| US-8962577-B2 | Controlled release formulations for the delivery of HIF-1 inhibitors | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-02-24 | — | — | US | disclosed |
| US-20130272994-A1 | Non-Linear Multiblock Copolymer-Drug Conjugates for the Delivery of Active Agents | THE JOHNS HOPKINS UNIVERSITY | 2013-10-17 | — | — | US | disclosed |
| US-20130274217-A1 | Controlled Release Formulations for the Delivery of HIF-1 Inhibitors | THE JOHNS HOPKINS UNIVERSITY | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11660349-B2 | Non-linear multiblock copolymer-drug conjugates for the delivery of active agents | VEGFA, UACA, PDE6A | MEN1 2861/4885THRB 3220/4885KMT2A 3704/4885 |
| US-20230364247-A1 | NON-LINEAR MULTIBLOCK COPOLYMER-DRUG CONJUGATES FOR THE DELIVERY OF ACTIVE AGENTS | VEGFA, UACA, PDE6A | MEN1 2861/4885THRB 3220/4885KMT2A 3704/4885 |
| US-20130274217-A1 | Controlled Release Formulations for the Delivery of HIF-1 Inhibitors | HIF1AN, HIF1A, EGLN3 | MEN1 602/4885THRB 1063/4885KMT2A 293/4885 |
| US-20130272994-A1 | Non-Linear Multiblock Copolymer-Drug Conjugates for the Delivery of Active Agents | VEGFA, UACA, PDE6A | MEN1 2861/4885THRB 3220/4885KMT2A 3704/4885 |
| US-20150141359-A1 | Controlled Release Formulations for the Delivery of HIF-1 Inhibitors | HIF1AN, HIF1A, EGLN3 | MEN1 602/4885THRB 1063/4885KMT2A 293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.