Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.47 |
| ▸ | FABP7 | O15540 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16591089 | 0.89 | KMT2A (0.41) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL21187928 | 0.88 | KMT2A (0.46) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL29456842 | 0.86 | KMT2A (0.51) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL10110895 | 0.86 | KMT2A (0.51) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL12704692 | 0.85 | KMT2A (0.55) | KMT2AFABP5FABP7EPHX2CASP3 | |
| SCHEMBL18132620 | 0.84 | HTR2A (0.43) | — | |
| SCHEMBL8453047 | 0.84 | KMT2A (0.50) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL23918256 | 0.83 | KMT2A (0.49) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL12128707 | 0.83 | KMT2A (0.49) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL7809928 | 0.83 | KMT2A (0.52) | KMT2AFABP5FABP7EPHX2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210145971-A1 | HSP90-TARGETING CONJUGATES AND FORMULATIONS THEREOF | Fusion Pharmaceuticals Inc. (CA) | 2021-05-20 | — | — | US | disclosed |
| US-9411058-B2 | Polymer composite based thermal neutron detectors | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2016-08-09 | — | — | US | disclosed |
| US-20150247938-A1 | POLYMER COMPOSITE BASED THERMAL NEUTRON DETECTORS | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2015-09-03 | — | — | US | disclosed |
| US-9086625-B2 | Resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2015-07-21 | — | — | US | disclosed |
| US-8796631-B2 | Polymer composite based thermal neutron detectors | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2014-08-05 | — | — | US | disclosed |
| US-8796631-B2 | Polymer composite based thermal neutron detectors | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2014-08-05 | — | — | US | disclosed |
| US-20140065545-A1 | RESIST COMPOSITION AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-03-06 | — | — | US | disclosed |
| US-20130270442-A1 | POLYMER COMPOSITE BASED THERMAL NEUTRON DETECTORS | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2013-10-17 | — | — | US | disclosed |
| US-20130270442-A1 | POLYMER COMPOSITE BASED THERMAL NEUTRON DETECTORS | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210145971-A1 | HSP90-TARGETING CONJUGATES AND FORMULATIONS THEREOF | HSP90AB1, HSP90B1, HSP90AA1 | KMT2A 4146/4885FABP5 1383/4885FABP7 344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.