Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ELANE | P08246 | 2/20 | 0.51 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16425838 | 1.00 | HTT (0.65) | HTTSMN1; SMN2GAAPKMTDP1 | |
| SCHEMBL12954962 | 1.00 | HTT (0.65) | HTTSMN1; SMN2GAAPKMTDP1 | |
| SCHEMBL16588321 | 1.00 | HTT (0.65) | HTTSMN1; SMN2GAAPKMTDP1 | |
| SCHEMBL14265612 | 1.00 | HTT (0.65) | HTTSMN1; SMN2GAAPKMTDP1 | |
| SCHEMBL12300188 | 0.95 | HTT (0.71) | HTTSMN1; SMN2GAAPKMTDP1 | |
| SCHEMBL15926451 | 0.95 | HTT (0.71) | HTTSMN1; SMN2GAAPKMTDP1 | |
| SCHEMBL21934883 | 0.95 | HTT (0.71) | HTTSMN1; SMN2GAAPKMTDP1 | |
| SCHEMBL16771243 | 0.95 | HTT (0.71) | HTTSMN1; SMN2GAAPKMTDP1 | |
| SCHEMBL15681791 | 0.95 | HTT (0.71) | HTTSMN1; SMN2GAAPKMTDP1 | |
| SCHEMBL17277953 | 0.95 | HTT (0.71) | HTTSMN1; SMN2GAAPKMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019030184-A1 | NEW CYCLOADDUCT PRECURSORS OF DIHALODIPHENYLSULFONES AND PREPARATIONS THEREOF | RHODIA OPERATIONS (FR) | 2019-02-14 | — | — | WO | disclosed |
| US-9045598-B2 | Process for producing aromatic polyether sulfones | BASF SE (DE) | 2015-06-02 | — | — | US | disclosed |
| US-20130274484-A1 | AROMATIC COMPOUNDS BEARING AT LEAST ONE PHOSPHONATE OR PHOSPHINATE GROUP, PREPARATION METHOD AND USES THEREOF | SOLVAY (CHINA) CO., LTD (CN) | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274484-A1 | AROMATIC COMPOUNDS BEARING AT LEAST ONE PHOSPHONATE OR PHOSPHINATE GROUP, PREPARATION METHOD AND USES THEREOF | PHOSPHO1, ATIC, ACP1 | HTT 2871/4885SMN1; SMN2 4335/4885GAA 1496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.