SCHEMBL15316264

SCHEMBL15316264

Cc1cc(N=Nc2ccc(N=Nc3ccc(N)cc3)c3ccc(S(=O)(=O)O)cc23)ccc1N=Nc1ccc(OC=O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHLPP2 Q6ZVD8 1/20 0.50
SENP2 Q9HC62 8/20 0.48
SENP1 Q9P0U3 7/20 0.48
SENP3 Q9H4L4 6/20 0.48
SUMO2 P61956 5/20 0.48
SUMO1 P63165 5/20 0.48
SENP7 Q9BQF6 5/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
HSD17B10 Q99714 2/20 0.48
ENPP2 Q13822 3/20 0.41
ATIC P31939 1/20 0.41
ALDH1A1 P00352 2/20 0.40
SLC7A11 Q9UPY5 2/20 0.40
HIF1A Q16665 1/20 0.40
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
TP53 P04637 1/20 0.39
APP P05067 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15316259 0.94 PHLPP2 (0.49) PHLPP2SENP2SENP1SENP3SUMO2
SCHEMBL16687357 0.92 PHLPP2 (0.47) PHLPP2SENP2SENP1SENP3SUMO2
SCHEMBL15316265 0.91 CYP2C9 (0.54) PHLPP2SENP2SENP1SENP3SUMO2
SCHEMBL9612278 0.89 PHLPP2 (0.58) PHLPP2SENP2SENP1SENP3SUMO2
SCHEMBL15316256 0.88 ENPP2 (0.51) PHLPP2SENP2SENP1SENP3SUMO2
SCHEMBL15316258 0.88 CYP2C9 (0.48) PHLPP2SENP2SENP1SENP3SUMO2
SCHEMBL15316252 0.86 PHLPP2 (0.55) PHLPP2SENP2SENP1SENP3SUMO2
SCHEMBL9612284 0.83 PHLPP2 (0.53) PHLPP2SENP2SENP1SENP3SUMO2
SCHEMBL9612298 0.83 PHLPP2 (0.57) PHLPP2SENP2SENP1SENP3SUMO2
SCHEMBL9174123 0.81 PHLPP2 (0.53) PHLPP2SENP2SENP1SENP3SUMO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9023118-B2 Azo dyes KEMIRA OYJ (FI) 2015-05-05 US disclosed
US-20130269124-A1 AZO DYES CHROMASCAPE, LLC 2013-10-17 US disclosed