Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL174964 | 0.92 | NAMPT (0.73) | NAMPTCYP2C9 | |
| SCHEMBL29635655 | 0.92 | NAMPT (0.73) | NAMPTCYP2C9 | |
| SCHEMBL29635730 | 0.91 | NAMPT (0.79) | NAMPTCYP2C9 | |
| SCHEMBL165700 | 0.91 | NAMPT (0.79) | NAMPTCYP2C9 | |
| SCHEMBL29635880 | 0.88 | NAMPT (0.76) | NAMPT | |
| SCHEMBL164519 | 0.88 | NAMPT (0.76) | NAMPT | |
| SCHEMBL29635795 | 0.88 | NAMPT (0.82) | NAMPTCYP2C9 | |
| SCHEMBL165642 | 0.88 | NAMPT (0.82) | NAMPTCYP2C9 | |
| SCHEMBL175270 | 0.87 | NAMPT (0.81) | NAMPTCYP2C9 | |
| SCHEMBL176173 | 0.87 | NAMPT (0.84) | NAMPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130273034-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | VALO EARLY DISCOVERY, INC. | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130273034-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | NAMPT, NNMT, NQO1 | NAMPT 1/4885CYP2C9 2180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.