Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 13/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10196674 | 0.88 | CYP19A1 (0.50) | KMT2ACYP19A1RECQL | |
| SCHEMBL15317634 | 0.81 | KMT2A (0.57) | ALDH1A1SMN1; SMN2MEN1HTTKMT2A | |
| SCHEMBL15317702 | 0.80 | KMT2A (0.48) | ALDH1A1SMN1; SMN2MEN1HTTKMT2A | |
| SCHEMBL15317651 | 0.80 | KMT2A (0.61) | ALDH1A1SMN1; SMN2MEN1HTTKMT2A | |
| SCHEMBL15317708 | 0.78 | KMT2A (0.58) | ALDH1A1SMN1; SMN2MEN1HTTKMT2A | |
| SCHEMBL15317801 | 0.78 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MEN1HTTKMT2A | |
| SCHEMBL14266348 | 0.77 | CYP19A1 (0.49) | ALDH1A1MEN1KMT2ACYP19A1 | |
| SCHEMBL15317650 | 0.77 | KMT2A (0.57) | ALDH1A1SMN1; SMN2MEN1HTTKMT2A | |
| SCHEMBL15317800 | 0.77 | KMT2A (0.59) | ALDH1A1SMN1; SMN2MEN1HTTKMT2A | |
| SCHEMBL17886712 | 0.75 | HPGD (0.56) | ALDH1A1SMN1; SMN2MEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9073892-B2 | Indazolyl triazol derivatives | MERCK SERONO S.A. (CH) | 2015-07-07 | — | — | US | disclosed |
| US-9073892-B2 | Indazolyl triazol derivatives | MERCK SERONO S.A. (CH) | 2015-07-07 | — | — | US | disclosed |
| US-20130274241-A1 | INDAZOLYL TRIAZOL DERIVATIVES | MERCK SERONO S.A. - INTELLECTUAL PROPERTY (CH) | 2013-10-17 | — | — | US | disclosed |
| US-20130274241-A1 | INDAZOLYL TRIAZOL DERIVATIVES | MERCK SERONO S.A. - INTELLECTUAL PROPERTY (CH) | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274241-A1 | INDAZOLYL TRIAZOL DERIVATIVES | NFATC1, IL5, CD4 | ALDH1A1 875/4885SMN1; SMN2 3843/4885MEN1 3827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.