SCHEMBL15318564

SCHEMBL15318564

CCCCC1C=CC(c2ccc(-c3ccc(OCCCc4ccc(C)cc4)cc3)cc2)CC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.36
DRD4 P21917 1/20 0.36
DRD3 P35462 1/20 0.36
FFAR4 Q5NUL3 2/20 0.36
CYP3A4 P08684 3/20 0.36
CYP2D6 P10635 3/20 0.36
KCNH2 Q12809 1/20 0.36
MEN1 O00255 2/20 0.36
ALDH1A1 P00352 2/20 0.36
KMT2A Q03164 2/20 0.36
HRH3 Q9Y5N1 1/20 0.36
USP2 O75604 1/20 0.36
LMNA P02545 1/20 0.36
MAPK1 P28482 1/20 0.36
CASP1 P29466 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SLCO1B3 Q9NPD5 1/20 0.36
SLCO1B1 Q9Y6L6 1/20 0.36
RAB9A P51151 1/20 0.35
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15316593 0.94 CYP3A4 (0.42) CYP3A4CYP2D6MEN1ALDH1A1KMT2A
SCHEMBL15220823 0.86 TSHR (0.40) FFAR4CYP3A4MEN1ALDH1A1KMT2A
SCHEMBL15220743 0.84 HRH3 (0.46) CYP3A4MEN1ALDH1A1KMT2AHRH3
SCHEMBL21182815 0.83 DRD2 (0.40) DRD2DRD4DRD3FFAR4KCNH2
SCHEMBL15219878 0.82 SPHK1 (0.40) CYP3A4MEN1ALDH1A1KMT2AHRH3
SCHEMBL15318593 0.81 SPHK1 (0.40) DRD2DRD4DRD3HRH3RAB9A
SCHEMBL21182712 0.80 MAOB (0.36) HRH3RAB9ACYP1A2
SCHEMBL21182887 0.78 HRH3 (0.41) FFAR4ALDH1A1HRH3MAPK1SMN1; SMN2
SCHEMBL15220942 0.77 KMT2A (0.36) MEN1ALDH1A1KMT2AHRH3RAB9A
SCHEMBL15316594 0.77 HRH3 (0.37) FFAR4HRH3LMNARAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9090825-B2 Cyclohexene-3,6-diyl compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-07-28 US disclosed
US-8956552-B2 Cyclohexene-3,6-diyl compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20130270480-A1 CYCLOHEXENE-3,6-DIYL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION 2013-10-17 US disclosed