Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15301947 | 0.77 | CLK2 (0.40) | — | |
| SCHEMBL30143698 | 0.77 | CLK2 (0.40) | — | |
| SCHEMBL15325678 | 0.75 | MAPT (0.35) | MAPT | |
| SCHEMBL15365948 | 0.74 | MAPT (0.39) | MAPT | |
| SCHEMBL15307252 | 0.72 | CLK2 (0.42) | — | |
| SCHEMBL17596983 | 0.72 | GBA1 (0.31) | — | |
| SCHEMBL19678629 | 0.70 | CSNK1D (0.43) | MAPT | |
| SCHEMBL15365445 | 0.69 | MAP4K4 (0.45) | MAPT | |
| SCHEMBL23360961 | 0.69 | GBA1 (0.46) | — | |
| SCHEMBL15365950 | 0.65 | MAPT (0.36) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760285-A1 | INDAZOLE INHIBITORS OF THE WNT SIGNAL PATHWAY AND THERAPEUTIC USES THEREOF | Samumed, LLC (US) | 2014-08-06 | — | — | EP | disclosed |
| WO-2013151708-A1 | INDAZOLE INHIBITORS OF THE WNT SIGNAL PATHWAY AND THERAPEUTIC USES THEREOF | SAMUMED, LLC (US) | 2013-10-10 | — | — | WO | disclosed |