Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12468923 | 0.90 | KMT2A (0.51) | KMT2AMEN1HRH1MAPTTP53 | |
| SCHEMBL12468902 | 0.85 | KMT2A (0.52) | KMT2AMEN1HRH1MAPTTP53 | |
| SCHEMBL15325979 | 0.82 | KMT2A (0.49) | KMT2AMEN1HRH1MAPTTP53 | |
| SCHEMBL12468730 | 0.82 | KMT2A (0.49) | KMT2AMEN1HRH1MAPTHSD17B10 | |
| SCHEMBL15325935 | 0.82 | KMT2A (0.49) | KMT2AMEN1HRH1MAPTTP53 | |
| SCHEMBL12469084 | 0.82 | KMT2A (0.49) | KMT2AMEN1HRH1MAPTTP53 | |
| SCHEMBL12469010 | 0.82 | KMT2A (0.49) | KMT2AMEN1HRH1MAPTTP53 | |
| SCHEMBL15325993 | 0.79 | KMT2A (0.45) | KMT2AMEN1HRH1MAPTTP53 | |
| SCHEMBL15325998 | 0.79 | KMT2A (0.45) | KMT2AMEN1HRH1MAPTTP53 | |
| SCHEMBL12468892 | 0.78 | MEN1 (0.53) | KMT2AMEN1HRH1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838534-A2 | SUBSTITUTED BENZAMIDES AND THEIR USES | The Board of Trustees of The Leland Stanford Junior University (US) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013155338-A2 | SUBSTITUTED BENZAMIDES AND THEIR USES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |