Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12468730 | 0.89 | KMT2A (0.49) | KMT2AMEN1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL12468923 | 0.87 | KMT2A (0.51) | KMT2AMEN1HSD17B10ALDH1A1HPGD | |
| SCHEMBL15323391 | 0.85 | KMT2A (0.49) | KMT2AMEN1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL12469084 | 0.80 | KMT2A (0.49) | KMT2AMEN1HSD17B10ALDH1A1HRH1 | |
| SCHEMBL15325935 | 0.80 | KMT2A (0.49) | KMT2AMEN1HSD17B10ALDH1A1HRH1 | |
| SCHEMBL15325979 | 0.80 | KMT2A (0.49) | KMT2AMEN1HSD17B10ALDH1A1HRH1 | |
| SCHEMBL12008412 | 0.77 | ALDH1A1 (0.77) | KMT2AMEN1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL15325998 | 0.77 | KMT2A (0.45) | KMT2AMEN1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL15325993 | 0.77 | KMT2A (0.45) | KMT2AMEN1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL12468892 | 0.76 | MEN1 (0.53) | KMT2AMEN1HSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627324-A2 | SUBSTITUTED BENZAMIDES AND THEIR USES | The Board of Trustees of The Leland Stanford Junior University (US) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012051117-A2 | SUBSTITUTED BENZAMIDES AND THEIR USES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2012-04-19 | — | — | WO | disclosed |