Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641130 | 0.88 | POLB (0.62) | POLBHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL11839824 | 0.88 | KMT2A (0.57) | POLBALDH1A1MEN1KMT2AHTT | |
| SCHEMBL694247 | 0.84 | CYP1A1 (0.53) | ALDH1A1LMNAMEN1KMT2AHTT | |
| SCHEMBL10965290 | 0.83 | MAPT (0.58) | POLBALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL4835086 | 0.82 | MEN1 (0.65) | POLBALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2933871 | 0.82 | KMT2A (0.63) | KDM4EALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL11763476 | 0.82 | KMT2A (0.59) | POLBALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL572726 | 0.82 | GAA (0.56) | HDAC3HDAC1HDAC2HDAC6KDM4E | |
| SCHEMBL733776 | 0.81 | EPHX2 (0.53) | HDAC1HDAC11HDAC8HDAC6HDAC4 | |
| SCHEMBL5306821 | 0.81 | SMN1; SMN2 (0.58) | POLBALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999130-B | Preparation method of o-nitroanilide compound | 湖北工业大学 | 2023-09-29 | — | — | CN | disclosed |
| CN-113999130-A | Preparation method of o-nitroanilide compound | 湖北工业大学 | 2022-02-01 | — | — | CN | disclosed |
| EP-2292585-B1 | Screening for solid forms by ultrasound crystallization and cocrystallization using ultrasound | APTUIT WEST LAFAYETTE LLC (US) | 2016-04-27 | — | — | EP | disclosed |
| US-8920559-B2 | Screening for solid forms by ultrasound crystallization and cocrystallization using ultrasound | APTUIT (WEST LAFAYETTE), LLC (US) | 2014-12-30 | — | — | US | disclosed |
| US-20110251426-A1 | SCREENING FOR SOLID FORMS BY ULTRASOUND CRYSTALLIZATION AND COCRYSTALLIZATION USING ULTRASOUND | S.S.C.I., INC. (US) | 2011-10-13 | — | — | US | disclosed |
| EP-2292585-A1 | Screening for solid forms by ultrasound crystallization and cocrystallization using ultrasound | APTUIT (KANSAS CITY), LLC (US) | 2011-03-09 | — | — | EP | disclosed |
| US-20070287194-A1 | Screening For Solid Forms By Ultrasound Crystallization And Cocrystallization Using Ultrasound | S.S.C.I., INC | 2007-12-13 | — | — | US | disclosed |
| US-20070051298-A1 | Method of searching for and generating high free energy forms | APTUIT (WEST LAFAYETTE), LLC | 2007-03-08 | — | — | US | disclosed |
| EP-1740930-A2 | SCREENING FOR SOLID FORMS BY ULTRASOUND CRYSTALLIZATION AND COCRYSTALLIZATION USING ULTRASOUND | S.S.C.I., Inc (US) | 2007-01-10 | — | — | EP | disclosed |
| US-7041169-B2 | Methods of generating and screening for high free energy forms in capillaries | S.S.C.I., INC. (US) | 2006-05-09 | — | — | US | disclosed |
| US-20040209304-A1 | Methods of searching for solid forms and screening a sample according to its forms | PURDUE RESEARCH FOUNDATION | 2004-10-21 | — | — | US | disclosed |
| US-20040139909-A1 | Methods of generating and screening for high free energy forms in capillaries | APOLLO ADMINISTRATIVE AGENCY LLC, AS SUCCESSOR AGENT | 2004-07-22 | — | — | US | disclosed |
| US-6750064-B2 | Methods of screening for possible solid forms | S.S.C.I. INC. | 2004-06-15 | — | — | US | disclosed |
| US-6642060-B2 | Generation of free energy forms of sample; obtain sample, solidify, isolate high energy form of sample | S.S.C.I., INC. | 2003-11-04 | — | — | US | disclosed |
| EP-1354079-A2 | METHODS OF SEARCHING FOR SOLID FORMS AND SCREENING A SAMPLE ACCORDING TO ITS FORMS | S.S.C.I., Inc (US) | 2003-10-22 | — | — | EP | disclosed |
| US-20030190758-A1 | Methods of searching for solid forms and screening a sample according to its forms | APOLLO ADMINISTRATIVE AGENCY LLC, AS SUCCESSOR AGENT | 2003-10-09 | — | — | US | disclosed |
| EP-1348046-A2 | METHOD OF SEARCHING FOR AND GENERATING HIGH FREE ENERGY FORMS | S.S.C.I., Inc (US) | 2003-10-01 | — | — | EP | disclosed |
| US-20020146842-A1 | Method of searching for and generating high free energy forms | APOLLO ADMINISTRATIVE AGENCY LLC, AS SUCCESSOR AGENT | 2002-10-10 | — | — | US | disclosed |
| WO-2002052919-A2 | METHODS OF SEARCHING FOR SOLID FORMS AND SCREENING A SAMPLE ACCORDING TO ITS FORMS | S.S.C.I., INC. (US) | 2002-07-11 | — | — | WO | disclosed |
| WO-2002054043-A2 | METHOD OF SEARCHING FOR AND GENERATING HIGH FREE ENERGY FORMS | S.S.C.I., INC. (US) | 2002-07-11 | — | — | WO | disclosed |