SCHEMBL2933871

SCHEMBL2933871

O=C(C[N+](=O)[O-])Nc1ccc(Br)cc1

nearest known ligand 0.71

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.63
MEN1 O00255 5/20 0.63
HPGD P15428 2/20 0.53
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
GBA1 P04062 1/20 0.52
MAPK1 P28482 1/20 0.52
ALDH1A1 P00352 4/20 0.50
MAPT P10636 2/20 0.50
HTT P42858 2/20 0.49
LMNA P02545 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
ALOX12 P18054 1/20 0.47
KDM4E B2RXH2 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL694247 0.84 CYP1A1 (0.53) KMT2AMEN1MAPK1ALDH1A1MAPT
SCHEMBL11763476 0.82 KMT2A (0.59) KMT2AMEN1HPGDNPC1RAB9A
SCHEMBL1532371 0.82 POLB (0.63) KMT2AMEN1ALDH1A1MAPTHTT
SCHEMBL572726 0.82 GAA (0.56) KMT2ANPC1RAB9AALDH1A1MAPT
SCHEMBL4835086 0.82 MEN1 (0.65) KMT2AMEN1HPGDNPC1RAB9A
SCHEMBL733776 0.81 EPHX2 (0.53) ALDH1A1MAPTHTTSMN1; SMN2L3MBTL1
SCHEMBL11347529 0.81 KMT2A (0.43) KMT2AMEN1HPGDNPC1RAB9A
SCHEMBL7428098 0.79 ALDH1A1 (0.60) KMT2AMEN1NPC1RAB9AALDH1A1
SCHEMBL10965290 0.79 MAPT (0.58) KMT2AMEN1NPC1RAB9AMAPK1
SCHEMBL1039601 0.79 KMT2A (0.76) KMT2AMEN1HPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1730102-B1 A NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3 , 4,4'-TETRAMINOBIPHENYL COUNCIL SCIENT IND RES (IN) 2010-09-22 EP claimed
EP-1730102-A1 A NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3 , 4,4'-TETRAMINOBIPHENYL Council of Scientific and Industrial Research (IN) 2006-12-13 EP claimed
WO-2005092839-A1 A NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3', 4,4'-TETRAMINOBIPHENYL COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-10-06 WO claimed
CN-112341431-A Heterocyclic compounds as FGFR4 inhibitors 齐鲁制药有限公司 2021-02-09 CN disclosed
EP-1730102-B1 A NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3 , 4,4'-TETRAMINOBIPHENYL COUNCIL SCIENT IND RES (IN) 2010-09-22 EP disclosed
EP-1730102-A1 A NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3 , 4,4'-TETRAMINOBIPHENYL Council of Scientific and Industrial Research (IN) 2006-12-13 EP disclosed
EP-1730102-A1 A NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3 , 4,4'-TETRAMINOBIPHENYL Council of Scientific and Industrial Research (IN) 2006-12-13 EP disclosed
US-6979749-B2 Catalytic process for the production of 3,3′, 4,4′-tetraminobiphenyl COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-12-27 US disclosed
WO-2005092839-A1 A NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3', 4,4'-TETRAMINOBIPHENYL COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-10-06 WO disclosed
WO-2005092839-A1 A NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3', 4,4'-TETRAMINOBIPHENYL COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-10-06 WO disclosed
US-20050215823-A1 NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3', 4,4'-TETRAMINOBIPHENYL COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-09-29 US disclosed
US-20050215823-A1 NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3', 4,4'-TETRAMINOBIPHENYL COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-09-29 US disclosed
EP-0299452-B1 Polyquinoxaline polymers, and articles comprising same AT & T CORP (US) 1994-10-05 EP disclosed
US-4914177-A Polyquinoxaline polymers, and articles comprising same AMERICAN TELEPHONE AND TELEGRAPH COMPANY (US) 1990-04-03 US disclosed
EP-0299452-A2 Polyquinoxaline polymers, and articles comprising same AT&T Corp. (US) 1989-01-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050215823-A1 NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3', 4,4'-TETRAMINOBIPHENYL NNMT, CBR3, POR KMT2A 130/4885MEN1 2108/4885HPGD 1008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.