Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.60 |
| ▸ | SLC1A2 | P43004 | 7/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.34 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.34 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.34 |
| ▸ | LAP3 | P28838 | 2/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL15323927 | 1.00 | SLC7A5 (0.60) | SLC7A5SLC1A2SLC1A3SLC1A1USP2 | |
| Leucine SCHEMBL15323880 | 0.92 | SLC7A5 (0.55) | SLC7A5SLC1A2SLC1A3SLC1A1USP2 | |
| Leucine SCHEMBL15323885 | 0.92 | SLC7A5 (0.55) | SLC7A5SLC1A2SLC1A3SLC1A1USP2 | |
| Leucine SCHEMBL15323703 | 0.91 | SLC7A5 (0.72) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL15323699 | 0.91 | SLC7A5 (0.72) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL28033141 | 0.89 | SLC7A5 (0.75) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL891924 | 0.89 | SLC7A5 (0.75) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL891921 | 0.89 | SLC7A5 (0.75) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Threonine SCHEMBL28929720 | 0.86 | USP2 (0.42) | SLC7A5SLC1A2SLC1A3SLC1A1USP2 | |
| Threonine SCHEMBL27545127 | 0.86 | USP2 (0.48) | SLC7A5SLC1A2SLC1A3SLC1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836832-A1 | EARLY TRIMESTER SCREENING FOR EARLY- AND LATE-ONSET PREECLAMPSIA | Wayne State University (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013155458-A1 | EARLY TRIMESTER SCREENING FOR EARLY- AND LATE-ONSET PREECLAMPSIA | WAYNE STATE UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |