Threonine

Threonine

SCHEMBL27545127

CC(O)C(N)C(=O)O.OCC(O)CO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.48
SLCO1B1 Q9Y6L6 1/20 0.48
SLC7A5 Q01650 2/20 0.48
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
OR51E2 Q9H255 1/20 0.39
TP53 P04637 1/20 0.38
SLC1A1 P43005 3/20 0.37
SLC1A3 P43003 3/20 0.37
SLC1A2 P43004 3/20 0.37
GABRP O00591 2/20 0.33
GABRD O14764 2/20 0.33
GABRA1 P14867 2/20 0.33
GABRB1 P18505 2/20 0.33
GABRG2 P18507 2/20 0.33
GABRB3 P28472 2/20 0.33
GABRA5 P31644 2/20 0.33
GABRA3 P34903 2/20 0.33
GABRA2 P47869 2/20 0.33
GABRB2 P47870 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Threonine SCHEMBL28929720 0.92 USP2 (0.42) USP2SLCO1B1SLC7A5ALDH1A1LMNA
Threonine SCHEMBL15571793 0.92 USP2 (0.42) USP2SLCO1B1SLC7A5ALDH1A1LMNA
Threonine SCHEMBL17140170 0.88 LMNA (0.50) USP2SLCO1B1SLC7A5LMNAOR51E2
Valine SCHEMBL528838 0.86 SLC7A5 (0.68) USP2SLCO1B1SLC7A5ALDH1A1LMNA
Valine SCHEMBL8524361 0.86 SLC7A5 (0.68) USP2SLCO1B1SLC7A5ALDH1A1LMNA
Valine SCHEMBL528839 0.86 SLC7A5 (0.68) USP2SLCO1B1SLC7A5ALDH1A1LMNA
Threonine SCHEMBL6040124 0.86 USP2 (0.59) USP2SLCO1B1SLC7A5LMNAOR51E2
Threonine SCHEMBL563849 0.86 SLC7A5 (0.52) USP2SLCO1B1SLC7A5OR51E2TP53
Threonine SCHEMBL15322831 0.86 USP2 (0.38) USP2SLCO1B1SLC7A5ALDH1A1LMNA
Threonine SCHEMBL6038228 0.85 SLC7A5 (0.63) USP2SLCO1B1SLC7A5ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105288634-A Preparation method of glycerin-amino acid deep eutectic solvent UNIV NANJING AGRICULTURAL 2016-02-03 CN disclosed
CN-1281732-C Production of agar-agar enzyme by Alteromonas sp.nov.SY 37-12 strain OCEAN UNIV CHINA (CN) 2006-10-25 CN disclosed