Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 19/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3111808 | 0.99 | SLC6A9 (0.62) | SLC6A9KCNH2KDM4E | |
| SCHEMBL15324302 | 0.89 | SLC6A9 (0.66) | SLC6A9KCNH2 | |
| SCHEMBL15323443 | 0.89 | SLC6A9 (0.60) | SLC6A9KCNH2 | |
| Hydrochloric Acid SCHEMBL3109083 | 0.89 | SLC6A9 (0.65) | SLC6A9KCNH2 | |
| Hydrochloric Acid SCHEMBL3109303 | 0.88 | SLC6A9 (0.59) | SLC6A9KCNH2 | |
| SCHEMBL15324301 | 0.88 | SLC6A9 (0.64) | SLC6A9KCNH2 | |
| SCHEMBL3094440 | 0.87 | SLC6A9 (0.61) | SLC6A9KCNH2 | |
| Hydrochloric Acid SCHEMBL3109078 | 0.87 | SLC6A9 (0.64) | SLC6A9KCNH2 | |
| Hydrochloric Acid SCHEMBL3105806 | 0.86 | SLC6A9 (0.60) | SLC6A9KCNH2 | |
| SCHEMBL7898302 | 0.84 | SLC6A9 (0.72) | SLC6A9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9067871-B2 | Aminotetraline derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2015-06-30 | — | — | US | claimed |
| US-8563617-B2 | Aminotetraline derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2013-10-22 | — | — | US | claimed |