SCHEMBL15324040

SCHEMBL15324040

NCCOc1ccc2c(c1)C(Cc1ccc(Cl)cc1)C(N)CC2

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 19/20 0.59
KCNH2 Q12809 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3094149 0.99 SLC6A9 (0.58) SLC6A9KCNH2
SCHEMBL3101513 0.89 SLC6A9 (0.71) SLC6A9KCNH2
SCHEMBL15323801 0.89 SLC6A9 (0.55) SLC6A9
SCHEMBL15324252 0.88 SLC6A9 (0.58) SLC6A9KCNH2
SCHEMBL3094440 0.88 SLC6A9 (0.61) SLC6A9KCNH2
Hydrochloric Acid SCHEMBL3094704 0.88 SLC6A9 (0.70) SLC6A9KCNH2
Hydrochloric Acid SCHEMBL3100047 0.88 SLC6A9 (0.54) SLC6A9
Hydrochloric Acid SCHEMBL3105982 0.87 SLC6A9 (0.57) SLC6A9KCNH2
Hydrochloric Acid SCHEMBL3105806 0.87 SLC6A9 (0.60) SLC6A9KCNH2
SCHEMBL15324060 0.87 SLC6A9 (0.65) SLC6A9KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2396296-B1 AMINOTETRALINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY ABBVIE DEUTSCHLAND (DE) 2016-05-25 EP claimed
US-9067871-B2 Aminotetraline derivatives, pharmaceutical compositions containing them, and their use in therapy AbbVie Deutschland GmbH & Co. KG (DE) 2015-06-30 US claimed
US-8563617-B2 Aminotetraline derivatives, pharmaceutical compositions containing them, and their use in therapy AbbVie Deutschland GmbH & Co. KG (DE) 2013-10-22 US claimed