Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14635725 | 0.73 | — | — | |
| SCHEMBL14636172 | 0.69 | — | — | |
| SCHEMBL131067 | 0.68 | SMN1; SMN2 (0.44) | SMN1; SMN2L3MBTL3L3MBTL1KDM1AMAOB | |
| SCHEMBL1827648 | 0.66 | SMN1; SMN2 (0.54) | SMN1; SMN2L3MBTL3L3MBTL1CYP2A13OPRL1 | |
| SCHEMBL9425142 | 0.66 | SMN1; SMN2 (0.54) | SMN1; SMN2L3MBTL3L3MBTL1CYP2A13OPRL1 | |
| SCHEMBL26112778 | 0.65 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL3L3MBTL1KDM1AMAOB | |
| SCHEMBL26112782 | 0.65 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL3L3MBTL1KDM1AMAOB | |
| SCHEMBL3168997 | 0.65 | — | — | |
| SCHEMBL132222 | 0.64 | SMN1; SMN2 (0.38) | SMN1; SMN2L3MBTL3L3MBTL1OPRL1HRH3 | |
| SCHEMBL35550 | 0.64 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL3L3MBTL1OPRL1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013149376-A1 | CHEMOKINE RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2013-10-10 | — | — | WO | claimed |
| WO-2013149376-A1 | CHEMOKINE RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2013-10-10 | — | — | WO | disclosed |