SCHEMBL1827648

SCHEMBL1827648

C1CCC(N2CCOCC2)C1

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.54
L3MBTL3 Q96JM7 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
HRH3 Q9Y5N1 6/20 0.42
OPRL1 P41146 2/20 0.41
ALDH1A1 P00352 2/20 0.39
CYP2A13 Q16696 1/20 0.39
HPGD P15428 1/20 0.39
PHGDH O43175 1/20 0.39
MGLL Q99685 1/20 0.39
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1824971 0.97 SMN1; SMN2 (0.52) SMN1; SMN2L3MBTL3L3MBTL1HRH3OPRL1
SCHEMBL35550 0.97 SMN1; SMN2 (0.52) SMN1; SMN2L3MBTL3L3MBTL1HRH3OPRL1
SCHEMBL5709151 0.97 SMN1; SMN2 (0.52) SMN1; SMN2L3MBTL3L3MBTL1HRH3OPRL1
SCHEMBL9425142 0.94 SMN1; SMN2 (0.54) SMN1; SMN2L3MBTL3L3MBTL1HRH3OPRL1
SCHEMBL26025479 0.93 SMN1; SMN2 (0.48) SMN1; SMN2L3MBTL3L3MBTL1HRH3OPRL1
Methylamine SCHEMBL28019730 0.91 SMN1; SMN2 (0.47) SMN1; SMN2L3MBTL3L3MBTL1HRH3OPRL1
SCHEMBL14907095 0.91 L3MBTL3 (0.49) SMN1; SMN2L3MBTL3L3MBTL1HRH3ALDH1A1
SCHEMBL25672747 0.89 L3MBTL3 (0.47) SMN1; SMN2L3MBTL3L3MBTL1HRH3ALDH1A1
SCHEMBL3168997 0.88
SCHEMBL26112782 0.88 SMN1; SMN2 (0.52) SMN1; SMN2L3MBTL3L3MBTL1HRH3OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115784474-A High-temperature-resistant high-pressure-resistant phosphorus-free sodium-free or low-sodium scale and corrosion inhibitor for boiler and preparation method and application thereof 上海聚焓能源科技有限公司 2023-03-14 CN claimed
CN-111517922-B Method for preparing 4-chloro-3,5-dimethylphenol 万华化学集团股份有限公司 2022-11-04 CN claimed
CN-111517922-A Method for preparing 4-chloro-3, 5-dimethylphenol 万华化学集团股份有限公司 2020-08-11 CN claimed
EP-2897970-B1 MACROLIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI SA (FR) 2016-07-13 EP claimed
US-20150210729-A1 MACROLIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI (FR) 2015-07-30 US claimed
EP-2897970-A1 MACROLIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI (FR) 2015-07-29 EP claimed
WO-2014044645-A1 MACROLIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI (FR) 2014-03-27 WO claimed
EP-4594309-A1 AZOLE MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYELINATION Genentech Inc. (US) 2025-08-06 EP disclosed
WO-2024073662-A1 AZOLE MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYELINATION GENENTECH, INC. (US) 2024-04-04 WO disclosed
US-11738487-B2 Processes for making molded flexible foams and flexible foams produced thereby COVESTRO LLC (US) 2023-08-29 US disclosed
CN-115784474-A High-temperature-resistant high-pressure-resistant phosphorus-free sodium-free or low-sodium scale and corrosion inhibitor for boiler and preparation method and application thereof 上海聚焓能源科技有限公司 2023-03-14 CN disclosed
CN-111517922-B Method for preparing 4-chloro-3,5-dimethylphenol 万华化学集团股份有限公司 2022-11-04 CN disclosed
CN-114805727-A Process for preparing molded flexible foams and flexible foams prepared therefrom 科思创有限公司 2022-07-29 CN disclosed
EP-0268975-A2 Process for the preparation of mono, bi and tricyclic amino acids, intermediary compounds and their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1988-06-01 EP disclosed
US-4666461-A Fuel treatment compositions THE LUBRIZOL CORPORATION (US) 1987-05-19 US disclosed
EP-0085510-B1 COMPOSITIONS FOR USE IN ALCOHOL AND ALCOHOL CONTAINING FUELS The Lubrizol Corporation (US) 1986-04-16 EP disclosed
US-4442286-A Preparation of amines by the reduction of imines with phosphorous acid PETROLITE CORPORATION (US) 1984-04-10 US disclosed
EP-0085510-A2 Compositions for use in alcohol and alcohol containing fuels The Lubrizol Corporation (US) 1983-08-10 EP disclosed
US-4384968-A TREATING GAS STREAM WITH MORPHOLINE OR SERIVATIVE BETZ LABORATORIES, INC. (US) 1983-05-24 US disclosed
US-3979380-A INOTROPIC ACTIVITY, CARDIAC STIMULANTS AMERICAN HOME PRODUCTS CORPORATION (US) 1976-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150210729-A1 MACROLIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF PCSK9, CYP51A1, ABCB11 SMN1; SMN2 1981/4885L3MBTL3 4769/4885L3MBTL1 4638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.