Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 13/20 | 0.52 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3105956 | 0.99 | SLC6A9 (0.51) | SLC6A9SCN3AKCNH2MAOBNQO2 | |
| SCHEMBL15323988 | 0.89 | SLC6A9 (0.51) | SLC6A9 | |
| Hydrochloric Acid SCHEMBL3098707 | 0.88 | SLC6A9 (0.51) | SLC6A9 | |
| SCHEMBL15324638 | 0.86 | SCN3A (0.48) | SLC6A9SCN3AKCNH2MAOB | |
| Hydrochloric Acid SCHEMBL3105949 | 0.85 | SCN3A (0.47) | SLC6A9SCN3AKCNH2MAOB | |
| SCHEMBL7894080 | 0.83 | SLC6A9 (0.63) | SLC6A9KCNH2NQO2MTNR1AMTNR1B | |
| SCHEMBL7894596 | 0.83 | SLC6A9 (0.79) | SLC6A9KCNH2 | |
| Hydrochloric Acid SCHEMBL3093981 | 0.82 | SLC6A9 (0.77) | SLC6A9KCNH2 | |
| SCHEMBL15324231 | 0.78 | SLC6A9 (0.48) | SLC6A9KCNH2MAOBNQO2MTNR1A | |
| SCHEMBL15323987 | 0.75 | SLC6A9 (0.47) | SLC6A9SCN3ANQO2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396296-B1 | AMINOTETRALINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | ABBVIE DEUTSCHLAND (DE) | 2016-05-25 | — | — | EP | claimed |
| US-9067871-B2 | Aminotetraline derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2015-06-30 | — | — | US | claimed |
| US-8563617-B2 | Aminotetraline derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2013-10-22 | — | — | US | claimed |