Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15323639 | 0.90 | PTGES (0.49) | PTGES | |
| SCHEMBL15324418 | 0.90 | PTGES (0.53) | PTGESCYP2D6 | |
| SCHEMBL2696497 | 0.83 | PTGES (0.59) | PTGES | |
| SCHEMBL15337265 | 0.82 | PTGES (0.78) | PTGES | |
| SCHEMBL15324602 | 0.81 | PTGES (0.77) | PTGESCYP2D6 | |
| SCHEMBL2699063 | 0.81 | PTGES (0.40) | PTGES | |
| SCHEMBL15324687 | 0.81 | PTGES (0.78) | PTGESCYP2D6 | |
| SCHEMBL15323982 | 0.80 | PTGES (0.51) | PTGES | |
| SCHEMBL2700066 | 0.80 | PTGES (0.57) | PTGES | |
| SCHEMBL2699069 | 0.80 | PTGES (0.56) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013153535-A1 | TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-10-17 | — | — | WO | claimed |
| WO-2013153535-A1 | TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-10-17 | — | — | WO | disclosed |
| WO-2013153535-A1 | TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-10-17 | — | — | WO | disclosed |