Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 8/20 | 1.00 |
| ▸ | CCR5 | P51681 | 4/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4146276 | 1.00 | CCR2 (1.00) | CCR2KCNH2CCR5 | |
| SCHEMBL13627578 | 1.00 | CCR2 (1.00) | CCR2KCNH2CCR5 | |
| SCHEMBL3326860 | 0.90 | CCR2 (0.86) | CCR2KCNH2CCR5 | |
| SCHEMBL13334954 | 0.90 | CCR2 (0.86) | CCR2KCNH2CCR5 | |
| SCHEMBL3030204 | 0.89 | CCR2 (0.91) | CCR2KCNH2CCR5 | |
| SCHEMBL13334959 | 0.88 | CCR2 (1.00) | CCR2KCNH2CCR5 | |
| SCHEMBL4141275 | 0.88 | CCR2 (0.79) | CCR2KCNH2CCR5 | |
| SCHEMBL3324613 | 0.88 | CCR2 (1.00) | CCR2KCNH2CCR5 | |
| SCHEMBL4151276 | 0.88 | CCR2 (1.00) | CCR2KCNH2CCR5 | |
| SCHEMBL4333693 | 0.88 | CCR2 (1.00) | CCR2KCNH2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8563582-B2 | 3-aminocyclopentanecarboxamides as modulators of chemokine receptors | INCYTE CORPORATION (US) | 2013-10-22 | — | — | US | disclosed |