Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12468977 | 0.86 | TP53 (0.74) | TP53MAPTPOLBLMNAGLA | |
| SCHEMBL15325968 | 0.81 | MAPT (0.55) | TP53MAPTPOLBLMNAGLA | |
| SCHEMBL15324908 | 0.80 | MAPT (0.60) | TP53MAPTPOLBLMNAHPGD | |
| SCHEMBL15323131 | 0.79 | MAPT (0.59) | TP53MAPTPOLBLMNASMN1; SMN2 | |
| SCHEMBL11359142 | 0.77 | POLB (0.78) | TP53MAPTPOLB | |
| SCHEMBL15325966 | 0.76 | MAPT (0.66) | TP53MAPTPOLBLMNA | |
| SCHEMBL27938282 | 0.76 | MAPT (0.68) | TP53MAPTPOLB | |
| SCHEMBL16558562 | 0.75 | MAPT (0.65) | TP53MAPTPOLBLMNA | |
| SCHEMBL15324481 | 0.75 | ALDH1A1 (0.57) | MAPTPOLBLMNAHPGDSMN1; SMN2 | |
| SCHEMBL12469249 | 0.75 | POLB (0.47) | TP53MAPTPOLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838534-A2 | SUBSTITUTED BENZAMIDES AND THEIR USES | The Board of Trustees of The Leland Stanford Junior University (US) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013155338-A2 | SUBSTITUTED BENZAMIDES AND THEIR USES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |