Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | THRB | P10828 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 7/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12468873 | 0.91 | MAPT (0.81) | MAPTTHRBPOLBTP53USP2 | |
| SCHEMBL27938291 | 0.91 | MAPT (0.70) | MAPTTHRBPOLBTP53USP2 | |
| SCHEMBL11356053 | 0.91 | MAPT (0.84) | MAPTTHRBPOLBTP53USP2 | |
| SCHEMBL15324597 | 0.90 | MAPT (0.71) | MAPTTHRBPOLBTP53USP2 | |
| SCHEMBL12469777 | 0.90 | MAPT (0.71) | MAPTTHRBPOLBTP53USP2 | |
| SCHEMBL11362002 | 0.90 | POLB (0.76) | MAPTTHRBPOLBTP53USP2 | |
| SCHEMBL15430795 | 0.89 | MAPT (0.68) | MAPTTHRBPOLBTP53USP2 | |
| SCHEMBL12469495 | 0.89 | MAPT (0.70) | MAPTTHRBPOLBTP53USP2 | |
| SCHEMBL12469088 | 0.88 | MAPT (0.69) | MAPTTHRBPOLBTP53USP2 | |
| SCHEMBL12468976 | 0.88 | MAPT (0.69) | MAPTTHRBPOLBTP53USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150329503-A1 | SUBSTITUTED BENZAMIDES AND THEIR USES | UNIV LELAND STANFORD JUNIOR (US) | 2015-11-19 | — | — | US | disclosed |
| US-20150329503-A1 | SUBSTITUTED BENZAMIDES AND THEIR USES | UNIV LELAND STANFORD JUNIOR (US) | 2015-11-19 | — | — | US | disclosed |
| WO-2013155338-A2 | SUBSTITUTED BENZAMIDES AND THEIR USES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329503-A1 | SUBSTITUTED BENZAMIDES AND THEIR USES | NISCH, BTD, NAAA | MAPT 2582/4885THRB 2141/4885POLB 970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.