⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15312419 | 0.85 | — | — | |
| SCHEMBL20567293 | 0.78 | — | — | |
| SCHEMBL2730009 | 0.74 | TSHR (0.41) | — | |
| SCHEMBL4541215 | 0.73 | TSHR (0.59) | — | |
| SCHEMBL19705410 | 0.71 | PAOX (0.45) | — | |
| Glutarate SCHEMBL4061457 | 0.71 | SLC22A6 (0.69) | — | |
| SCHEMBL225702 | 0.71 | TSHR (0.71) | — | |
| Adipic Acid SCHEMBL27801856 | 0.71 | LMNA (0.69) | — | |
| SCHEMBL756105 | 0.71 | TSHR (0.71) | — | |
| Adipic Acid SCHEMBL851390 | 0.71 | LMNA (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150057243-A1 | Compositions and Methods for the Inhibition of Methyltransferases | NORTHERN UNIVERSITY (US) | 2015-02-26 | — | — | US | disclosed |
| US-20150057243-A1 | Compositions and Methods for the Inhibition of Methyltransferases | NORTHERN UNIVERSITY (US) | 2015-02-26 | — | — | US | disclosed |
| WO-2013151975-A1 | COMPOSITIONS AND METHODS FOR THE INHIBITION OF METHYLTRANSFERASES | NORTHEASTERN UNIVERSITY (US) | 2013-10-10 | — | — | WO | disclosed |