Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15327101 | 0.83 | SMN1; SMN2 (0.41) | RAB9ANPC1L3MBTL1HPGDKDM4E | |
| SCHEMBL15327047 | 0.82 | KDM4E (0.56) | RAB9ANPC1ADORA2AADORA1L3MBTL1 | |
| SCHEMBL2199705 | 0.81 | EGLN1 (0.61) | RAB9ANPC1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL15327067 | 0.79 | KDM4E (0.59) | TSHRCYP1A2CYP2D6CYP2C19HPGD | |
| SCHEMBL15327091 | 0.78 | NAMPT (0.46) | RAB9ANPC1ADORA2AADORA1L3MBTL1 | |
| SCHEMBL15327132 | 0.78 | EGLN1 (0.62) | ADORA2AHTTKMT2AMAPT | |
| SCHEMBL15327109 | 0.77 | HTT (0.58) | RAB9ANPC1SMN1; SMN2MAPK1HTT | |
| SCHEMBL15327081 | 0.77 | ADORA2A (0.48) | RAB9ANPC1ADORA2AADORA1L3MBTL1 | |
| SCHEMBL15327127 | 0.77 | OPRK1 (0.42) | RAB9ANPC1KDM4EALDH1A1MEN1 | |
| SCHEMBL15327100 | 0.76 | HPGD (0.60) | RAB9ANPC1TSHRHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519504-B1 | NEW SECONDARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES. | POLICHEM SA (LU) | 2014-03-19 | — | — | EP | claimed |
| EP-2519503-B1 | SECONDARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES FOR USE AS ANTIFUNGAL AGENTS | POLICHEM SA (LU) | 2013-10-23 | — | — | EP | claimed |