Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3062216 | 1.00 | CTSS (0.55) | CTSS | |
| SCHEMBL15327164 | 1.00 | CTSS (0.55) | CTSS | |
| SCHEMBL3073501 | 0.91 | CTSS (0.57) | CTSS | |
| SCHEMBL3067607 | 0.91 | CTSS (0.57) | CTSS | |
| SCHEMBL3067610 | 0.91 | CTSS (0.57) | CTSS | |
| SCHEMBL3067616 | 0.91 | CTSS (0.57) | CTSS | |
| SCHEMBL15327178 | 0.90 | CTSS (0.57) | CTSS | |
| SCHEMBL3076402 | 0.90 | CTSS (0.57) | CTSS | |
| SCHEMBL15327177 | 0.90 | CTSS (0.57) | CTSS | |
| SCHEMBL3056108 | 0.90 | CTSS (0.57) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421826-B1 | PROLINE DERIVATIVES AS CATHEPSIN INHIBITORS | HOFFMANN LA ROCHE (CH) | 2013-10-23 | — | — | EP | disclosed |