Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2105201 | 0.89 | CTSS (0.64) | CTSS | |
| SCHEMBL15327434 | 0.84 | CTSS (0.53) | CTSS | |
| SCHEMBL15327446 | 0.84 | CTSS (0.52) | CTSS | |
| SCHEMBL15327217 | 0.82 | CTSS (0.59) | CTSS | |
| SCHEMBL15327304 | 0.82 | CTSS (0.55) | CTSS | |
| SCHEMBL15327419 | 0.81 | CTSS (0.55) | CTSS | |
| SCHEMBL2105522 | 0.81 | CTSS (0.63) | CTSS | |
| Hydrochloric Acid SCHEMBL695460 | 0.81 | CTSS (0.62) | CTSS | |
| SCHEMBL15327585 | 0.78 | CTSS (0.51) | CTSS | |
| SCHEMBL15327441 | 0.78 | CTSS (0.51) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421826-B1 | PROLINE DERIVATIVES AS CATHEPSIN INHIBITORS | HOFFMANN LA ROCHE (CH) | 2013-10-23 | — | — | EP | claimed |