Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15327385 | 1.00 | CTSS (0.47) | CTSSCTSLCTSB | |
| SCHEMBL15327383 | 0.91 | CTSS (0.49) | CTSSCTSLCTSB | |
| SCHEMBL15327369 | 0.91 | CTSS (0.49) | CTSSCTSLCTSB | |
| SCHEMBL15327564 | 0.89 | CTSS (0.48) | CTSSCTSLCTSB | |
| SCHEMBL696217 | 0.89 | CTSS (0.58) | CTSSCTSLCTSB | |
| SCHEMBL695551 | 0.89 | CTSS (0.58) | CTSSCTSLCTSB | |
| SCHEMBL15327220 | 0.89 | CTSS (0.52) | CTSSCTSLCTSB | |
| SCHEMBL15327556 | 0.88 | CTSS (0.51) | CTSSCTSLCTSB | |
| SCHEMBL15327337 | 0.88 | CTSS (0.51) | CTSSCTSL | |
| SCHEMBL15327447 | 0.88 | CTSS (0.37) | CTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421826-B1 | PROLINE DERIVATIVES AS CATHEPSIN INHIBITORS | HOFFMANN LA ROCHE (CH) | 2013-10-23 | — | — | EP | claimed |