Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 8/20 | 0.85 |
| ▸ | ENPP2 | Q13822 | 8/20 | 0.85 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.85 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.75 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.74 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.74 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.74 |
| ▸ | CES2 | O00748 | 1/20 | 0.74 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.74 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.74 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.71 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.71 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.71 |
| ▸ | PRKCA | P17252 | 1/20 | 0.71 |
| ▸ | SELP | P16109 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30555867 | 1.00 | LPAR1 (0.85) | LPAR1ENPP2LPAR3SMN1; SMN2S1PR1 | |
| SCHEMBL3817083 | 1.00 | LPAR1 (0.85) | LPAR1ENPP2LPAR3SMN1; SMN2S1PR1 | |
| SCHEMBL235478 | 1.00 | LPAR1 (0.85) | LPAR1ENPP2LPAR3SMN1; SMN2S1PR1 | |
| SCHEMBL7700077 | 1.00 | LPAR1 (0.85) | LPAR1ENPP2LPAR3SMN1; SMN2S1PR1 | |
| SCHEMBL173282 | 1.00 | LPAR1 (0.85) | LPAR1ENPP2LPAR3SMN1; SMN2S1PR1 | |
| SCHEMBL15328011 | 1.00 | LPAR1 (0.85) | LPAR1ENPP2LPAR3SMN1; SMN2S1PR1 | |
| SCHEMBL7698286 | 1.00 | LPAR1 (0.85) | LPAR1ENPP2LPAR3SMN1; SMN2S1PR1 | |
| SCHEMBL200646 | 1.00 | LPAR1 (0.85) | LPAR1ENPP2LPAR3SMN1; SMN2S1PR1 | |
| SCHEMBL17549876 | 1.00 | LPAR1 (0.85) | LPAR1ENPP2LPAR3SMN1; SMN2S1PR1 | |
| SCHEMBL30555910 | 1.00 | LPAR1 (0.85) | LPAR1ENPP2LPAR3SMN1; SMN2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130281409-A1 | Myelin Sheath Fatty Acids that Resolve Neuroinflammation | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2013-10-24 | — | — | US | claimed |
| US-20130281409-A1 | Myelin Sheath Fatty Acids that Resolve Neuroinflammation | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2013-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281409-A1 | Myelin Sheath Fatty Acids that Resolve Neuroinflammation | MAG, FABP7, PMP22 | LPAR1 22/4885ENPP2 220/4885LPAR3 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.