Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 8/20 | 0.85 |
| ▸ | ENPP2 | Q13822 | 8/20 | 0.85 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.85 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.75 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.74 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.74 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.74 |
| ▸ | CES2 | O00748 | 1/20 | 0.74 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.74 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.74 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.71 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.71 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.71 |
| ▸ | PRKCA | P17252 | 1/20 | 0.71 |
| ▸ | SELP | P16109 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30555867 | 1.00 | LPAR1 (0.85) | LPAR1ENPP2LPAR3SMN1; SMN2S1PR1 | |
| SCHEMBL3817083 | 1.00 | LPAR1 (0.85) | LPAR1ENPP2LPAR3SMN1; SMN2S1PR1 | |
| SCHEMBL235478 | 1.00 | LPAR1 (0.85) | LPAR1ENPP2LPAR3SMN1; SMN2S1PR1 | |
| SCHEMBL7700077 | 1.00 | LPAR1 (0.85) | LPAR1ENPP2LPAR3SMN1; SMN2S1PR1 | |
| SCHEMBL173282 | 1.00 | LPAR1 (0.85) | LPAR1ENPP2LPAR3SMN1; SMN2S1PR1 | |
| SCHEMBL15328013 | 1.00 | LPAR1 (0.85) | LPAR1ENPP2LPAR3SMN1; SMN2S1PR1 | |
| SCHEMBL15328011 | 1.00 | LPAR1 (0.85) | LPAR1ENPP2LPAR3SMN1; SMN2S1PR1 | |
| SCHEMBL200646 | 1.00 | LPAR1 (0.85) | LPAR1ENPP2LPAR3SMN1; SMN2S1PR1 | |
| SCHEMBL17549876 | 1.00 | LPAR1 (0.85) | LPAR1ENPP2LPAR3SMN1; SMN2S1PR1 | |
| SCHEMBL30555910 | 1.00 | LPAR1 (0.85) | LPAR1ENPP2LPAR3SMN1; SMN2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344576-B1 | CATIONIC PHOSPHATIDES AND GLYCERIDES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2002-02-05 | — | — | US | disclosed |