Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 10/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.50 |
| ▸ | APC | P25054 | 3/20 | 0.47 |
| ▸ | CCKBR | P32239 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15328485 | 0.91 | OPRD1 (0.50) | OPRD1OPRM1OPRK1APC | |
| SCHEMBL15328483 | 0.91 | OPRD1 (0.50) | OPRD1OPRM1OPRK1APC | |
| SCHEMBL15328393 | 0.90 | OPRD1 (0.49) | OPRD1OPRM1OPRK1APCCCKBR | |
| SCHEMBL15344090 | 0.88 | PTPN1 (0.46) | OPRD1OPRM1OPRK1APC | |
| SCHEMBL15328503 | 0.85 | ACE (0.44) | OPRD1OPRM1OPRK1APC | |
| SCHEMBL15328504 | 0.85 | ACE (0.44) | OPRD1OPRM1OPRK1APC | |
| SCHEMBL17082288 | 0.85 | OPRD1 (0.47) | OPRD1OPRM1OPRK1APC | |
| SCHEMBL15344184 | 0.85 | OPRD1 (0.47) | OPRD1OPRM1OPRK1APC | |
| SCHEMBL17082284 | 0.85 | OPRD1 (0.47) | OPRD1OPRM1OPRK1APC | |
| SCHEMBL15328267 | 0.84 | ACE (0.45) | OPRD1OPRM1OPRK1APC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169295-B2 | Macrocycles and macrocycle stabilized peptides | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-10-27 | — | — | US | disclosed |
| US-20130281657-A1 | MACROCYCLES AND MACROCYCLE STABILIZED PEPTIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281657-A1 | MACROCYCLES AND MACROCYCLE STABILIZED PEPTIDES | PTMS, VIP, MTPN | OPRD1 4530/4885OPRM1 4478/4885OPRK1 4371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.