Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 7/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15328477 | 1.00 | SLC7A5 (0.60) | SLC7A5HSD17B10USP2KDM4EALOX15 | |
| SCHEMBL17082311 | 0.82 | SLC7A5 (0.53) | SLC7A5HSD17B10USP2KDM4EALOX15 | |
| SCHEMBL10074960 | 0.77 | SMN1; SMN2 (0.50) | SLC7A5HSD17B10USP2KDM4EALOX15 | |
| SCHEMBL7425388 | 0.77 | SMN1; SMN2 (0.50) | SLC7A5HSD17B10USP2KDM4EALOX15 | |
| SCHEMBL10074961 | 0.77 | SMN1; SMN2 (0.50) | SLC7A5HSD17B10USP2KDM4EALOX15 | |
| SCHEMBL5324730 | 0.76 | SLC7A5 (1.00) | SLC7A5HSD17B10USP2KDM4EALOX15 | |
| SCHEMBL11077965 | 0.76 | SLC7A5 (0.84) | SLC7A5HSD17B10USP2KDM4EALOX15 | |
| SCHEMBL2299795 | 0.76 | SLC7A5 (1.00) | SLC7A5HSD17B10USP2KDM4EALOX15 | |
| SCHEMBL5321753 | 0.74 | SLC7A5 (0.71) | SLC7A5HSD17B10USP2KDM4EALOX15 | |
| SCHEMBL20912657 | 0.74 | SLC7A5 (0.71) | SLC7A5HSD17B10USP2KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169295-B2 | Macrocycles and macrocycle stabilized peptides | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-10-27 | — | — | US | disclosed |
| EP-2627662-B1 | METHODS FOR PREPARING MACROCYCLES AND MACROCYCLE STABILIZED PEPTIDES | BRISTOL MYERS SQUIBB CO (US) | 2015-09-16 | — | — | EP | disclosed |
| US-20130281657-A1 | MACROCYCLES AND MACROCYCLE STABILIZED PEPTIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281657-A1 | MACROCYCLES AND MACROCYCLE STABILIZED PEPTIDES | PTMS, VIP, MTPN | SLC7A5 96/4885HSD17B10 3722/4885USP2 3830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.