Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 8/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | USP2 | O75604 | 3/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | RECQL | P46063 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | EGFR | P00533 | 1/20 | 0.65 |
| ▸ | LCK | P06239 | 1/20 | 0.65 |
| ▸ | FYN | P06241 | 1/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | ALPI | P09923 | 1/20 | 0.60 |
| ▸ | XIAP | P98170 | 1/20 | 0.60 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324730 | 1.00 | SLC7A5 (1.00) | SLC7A5ALOX15HIF1AHSD17B10USP2 | |
| SCHEMBL11077965 | 0.91 | SLC7A5 (0.84) | SLC7A5ALOX15HIF1AHSD17B10USP2 | |
| SCHEMBL9273339 | 0.85 | SLC7A5 (0.73) | SLC7A5ALOX15HIF1AHSD17B10USP2 | |
| SCHEMBL29585153 | 0.83 | SLC7A5 (0.71) | SLC7A5ALOX15HIF1AHSD17B10USP2 | |
| SCHEMBL20912657 | 0.83 | SLC7A5 (0.71) | SLC7A5ALOX15HIF1AHSD17B10USP2 | |
| SCHEMBL1248325 | 0.83 | SLC7A5 (0.71) | SLC7A5ALOX15HIF1AHSD17B10USP2 | |
| SCHEMBL5321753 | 0.83 | SLC7A5 (0.71) | SLC7A5ALOX15HIF1AHSD17B10USP2 | |
| Levodopa SCHEMBL896629 | 0.83 | SLC7A5 (0.87) | SLC7A5ALOX15HIF1AHSD17B10USP2 | |
| SCHEMBL20912658 | 0.83 | SLC7A5 (0.71) | SLC7A5ALOX15HIF1AHSD17B10USP2 | |
| SCHEMBL1249808 | 0.83 | SLC7A5 (0.71) | SLC7A5ALOX15HIF1AHSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003791-B2 | Boronic ester and acid compounds, synthesis and uses | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-08-23 | — | — | US | disclosed |
| US-20090247731-A1 | BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-10-01 | — | — | US | disclosed |
| US-20040101523-A1 | Renal-selective prodrugs for control of renal smpathetic nerve activity in the treatment of hypertension | G.D. SEARLE & CO. | 2004-05-27 | — | — | US | disclosed |
| EP-0403600-A4 | DEPROTECTION OF PROTECTED PEPTIDES | — | 1991-03-13 | — | — | EP | disclosed |
| EP-0403600-A1 | DEPROTECTION OF PROTECTED PEPTIDES | THE ROCKEFELLER UNIVERSITY (US) | 1990-12-27 | — | — | EP | disclosed |
| WO-1990002138-A1 | DEPROTECTION OF PROTECTED PEPTIDES | THE ROCKEFELLER UNIVERSITY (US) | 1990-03-08 | — | — | WO | disclosed |
| US-4507230-A | DETACHING RESINS FROM PEPTIDES | RESEARCH CORPORATION (US) | 1985-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247731-A1 | BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES | BCL6, BCAP31, CD79B | SLC7A5 217/4885ALOX15 2840/4885HIF1A 2910/4885 |
| US-20040101523-A1 | Renal-selective prodrugs for control of renal smpathetic nerve activity in the treatment of hypertension | GLS, DBH, APEH | SLC7A5 219/4885ALOX15 1824/4885HIF1A 1733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.