Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LSS | P48449 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2245630 | 0.95 | THRB (0.59) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL25796355 | 0.93 | THRB (0.65) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL12172632 | 0.92 | THRB (0.63) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL12172633 | 0.91 | TSHR (0.63) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL723159 | 0.91 | TSHR (0.63) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL14907526 | 0.91 | TSHR (0.63) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL13289971 | 0.91 | TSHR (0.63) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL20082190 | 0.90 | TSHR (0.51) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL20082224 | 0.90 | TSHR (0.51) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL20082220 | 0.90 | TSHR (0.51) | THRBTSHRALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1754768-B1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICALLY ANISOTROPIC BODY | DAINIPPON INK & CHEMICALS (JP) | 2011-03-30 | — | — | EP | disclosed |
| US-7449223-B2 | containing an additive that improves the level of defects in the vicinity of the air interface for an optically anisotropic medium that exhibits either tilted alignment or horizontal alignment | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2008-11-11 | — | — | US | disclosed |
| US-20070170394-A1 | Polymerizable liquid crystal composition and optically anisotropic medium | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2007-07-26 | — | — | US | disclosed |
| EP-1754768-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICALLY ANISOTROPIC BODY | Dainippon Ink and Chemicals, Incorporated (JP) | 2007-02-21 | — | — | EP | disclosed |