SCHEMBL1532903

SCHEMBL1532903

C=CC(=O)OCCP(=O)(O)CCOC(=O)C=C

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.56
ALDH1A1 P00352 5/20 0.56
TP53 P04637 3/20 0.56
HIF1A Q16665 3/20 0.56
CYP3A4 P08684 2/20 0.56
HSD17B10 Q99714 1/20 0.56
HPGD P15428 1/20 0.50
THRB P10828 2/20 0.42
MAPK1 P28482 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
LPAR2 Q9HBW0 1/20 0.31
LPAR3 Q9UBY5 1/20 0.31
ATM Q13315 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8089941 0.89 TSHR (0.65) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL41764 0.87 TSHR (0.56) TSHRALDH1A1TP53HIF1ACYP3A4
Phosphoric Acid SCHEMBL25381640 0.85 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
Phosphoric Acid SCHEMBL6886898 0.84 TSHR (0.70) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28877044 0.83 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL21052653 0.81 TSHR (0.70) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9846963 0.81 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
Potassium Ion SCHEMBL141811 0.81 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL21102734 0.80 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL3278847 0.80 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1960490-B1 MULTIPHASE ACRYLIC ADHESIVES HUNTSMANN ADVANCED MAT LICENSING (SWITZERLAND) GMBH (CH) 2017-02-22 EP disclosed
US-8552091-B2 Multiphase acrylic adhesives HUNTSMAN INTERNATIONAL LLC (US) 2013-10-08 US disclosed
US-20120261071-A1 Multiphase Acrylic Adhesives HUNTSMAN INTERNATIONAL LLC (US) 2012-10-18 US disclosed
US-8235251-B2 Multiphase acrylic adhesives HUNTSMAN INTERNATIONAL LLC (US) 2012-08-07 US disclosed
EP-2363443-A2 Multiphase acrylic adhesives Huntsman Advanced Materials (Switzerland) GmbH (CH) 2011-09-07 EP disclosed
US-20110139819-A1 MULTIPHASE ACRYLIC ADHESIVES HUNTSMAN INTERNATIONAL LLC (US) 2011-06-16 US disclosed
US-7910636-B2 Multiphase acrylic adhesives HUNTSMAN INTERNATIONAL LLC (US) 2011-03-22 US disclosed
US-20080302479-A1 Multiphase Acrylic Adhesives HUNTSMAN INTERNATIONAL LLC (US) 2008-12-11 US disclosed
EP-1960490-A1 MULTIPHASE ACRYLIC ADHESIVES Huntsman Advanced Materials (Switzerland) GmbH (CH) 2008-08-27 EP disclosed
WO-2007068625-A1 MULTIPHASE ACRYLIC ADHESIVES HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2007-06-21 WO disclosed