Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | KCNQ2 | O43526 | 5/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.62 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555188 | 0.99 | KMT2A (0.65) | KMT2AKCNQ2GAAPKMNPSR1 | |
| SCHEMBL29951675 | 0.92 | KCNQ2 (0.70) | KMT2AKCNQ2GAAPKMNPSR1 | |
| SCHEMBL29957211 | 0.90 | KMT2A (0.68) | KMT2AKCNQ2GAAPKMNPSR1 | |
| SCHEMBL29955086 | 0.85 | KCNQ2 (0.74) | KMT2AKCNQ2GAAPKMNPSR1 | |
| SCHEMBL29957640 | 0.84 | KMT2A (0.72) | KMT2AKCNQ2GAAPKMNPSR1 | |
| SCHEMBL13167010 | 0.80 | KCNQ2 (1.00) | KMT2AKCNQ2GAAPKMNPSR1 | |
| SCHEMBL21665202 | 0.80 | HTT (0.60) | KMT2AGAAALDH1A1MEN1KDM4E | |
| SCHEMBL4318899 | 0.79 | KCNQ2 (0.68) | KMT2AKCNQ2GAAPKMNPSR1 | |
| SCHEMBL22897679 | 0.78 | KCNQ2 (0.68) | KMT2AKCNQ2GAAPKMNPSR1 | |
| SCHEMBL29559749 | 0.78 | KCNQ2 (0.68) | KMT2AKCNQ2GAAPKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |