Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | KCNQ2 | O43526 | 5/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.60 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | XBP1 | P17861 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951675 | 0.99 | KCNQ2 (0.70) | KMT2AKCNQ2GAAPKMNPSR1 | |
| SCHEMBL2555188 | 0.92 | KMT2A (0.65) | KMT2AKCNQ2GAAPKMNPSR1 | |
| SCHEMBL15329587 | 0.90 | KMT2A (0.67) | KMT2AKCNQ2GAAPKMNPSR1 | |
| SCHEMBL29957640 | 0.88 | KMT2A (0.72) | KMT2AKCNQ2GAAPKMNPSR1 | |
| SCHEMBL29955086 | 0.87 | KCNQ2 (0.74) | KMT2AKCNQ2GAAPKMNPSR1 | |
| SCHEMBL29559749 | 0.82 | KCNQ2 (0.68) | KMT2AKCNQ2GAAPKMNPSR1 | |
| SCHEMBL22897679 | 0.82 | KCNQ2 (0.68) | KMT2AKCNQ2GAAPKMNPSR1 | |
| SCHEMBL19421306 | 0.82 | KCNQ2 (0.60) | KMT2AKCNQ2GAAPKMNPSR1 | |
| SCHEMBL13167010 | 0.81 | KCNQ2 (1.00) | KMT2AKCNQ2GAAPKMNPSR1 | |
| SCHEMBL10669472 | 0.81 | KCNQ2 (0.62) | KMT2AKCNQ2GAAPKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |