Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.54 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.54 |
| ▸ | PIM3 | Q86V86 | 10/20 | 0.48 |
| ▸ | PIM1 | P11309 | 8/20 | 0.48 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15332515 | 0.85 | TRIM24 (0.51) | TRIM24TRIM33PIM3PIM1PIM2 | |
| SCHEMBL29952544 | 0.82 | TRIM24 (0.54) | TRIM24TRIM33PIM3PIM1PIM2 | |
| SCHEMBL15332180 | 0.80 | TRIM24 (0.55) | TRIM24TRIM33PIM3PIM1PIM2 | |
| SCHEMBL29639077 | 0.78 | TRIM24 (0.50) | TRIM24TRIM33PIM3PIM1PIM2 | |
| SCHEMBL28578011 | 0.78 | TRIM24 (0.50) | TRIM24TRIM33PIM3PIM1PIM2 | |
| SCHEMBL29639078 | 0.78 | TRIM24 (0.50) | TRIM24TRIM33PIM3PIM1PIM2 | |
| SCHEMBL1092989 | 0.77 | TRIM24 (0.64) | TRIM24TRIM33PIM3PIM1PIM2 | |
| SCHEMBL31370448 | 0.76 | NR4A2 (0.47) | NR3C1PGRNR3C2ARNR4A2 | |
| SCHEMBL671445 | 0.76 | CYP2A6 (0.54) | PIM3PIM1PIM2NR4A2CYP2A6 | |
| SCHEMBL29955201 | 0.75 | TRIM24 (0.50) | TRIM24TRIM33PIM3PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |