Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.54 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.54 |
| ▸ | IMPDH2 | P12268 | 5/20 | 0.50 |
| ▸ | PIM3 | Q86V86 | 7/20 | 0.47 |
| ▸ | PIM1 | P11309 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955201 | 0.84 | TRIM24 (0.50) | TRIM24TRIM33IMPDH2PIM3PIM1 | |
| SCHEMBL15329804 | 0.82 | TRIM24 (0.54) | TRIM24TRIM33IMPDH2PIM3PIM1 | |
| SCHEMBL15332515 | 0.77 | TRIM24 (0.51) | TRIM24TRIM33IMPDH2PIM3PIM1 | |
| SCHEMBL29954181 | 0.76 | CYP2A6 (0.54) | IMPDH2PIM3PIM1KMT2APIM2 | |
| SCHEMBL28578011 | 0.75 | TRIM24 (0.50) | TRIM24TRIM33IMPDH2PIM3PIM1 | |
| SCHEMBL29639078 | 0.75 | TRIM24 (0.50) | TRIM24TRIM33IMPDH2PIM3PIM1 | |
| SCHEMBL29639077 | 0.75 | TRIM24 (0.50) | TRIM24TRIM33IMPDH2PIM3PIM1 | |
| SCHEMBL29954763 | 0.75 | TRIM24 (0.70) | TRIM24TRIM33IMPDH2PIM3PIM1 | |
| SCHEMBL15332180 | 0.74 | TRIM24 (0.55) | TRIM24TRIM33IMPDH2PIM3PIM1 | |
| SCHEMBL29955386 | 0.72 | TRIM24 (0.66) | TRIM24TRIM33IMPDH2PIM3PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |