Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 5/20 | 0.57 |
| ▸ | TUBB | P07437 | 5/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.57 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.57 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.57 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.57 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.57 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.57 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | GAA | P10253 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4877545 | 0.89 | KDM4E (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29956404 | 0.87 | KDM4E (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1429238 | 0.87 | KDM4E (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7250379 | 0.87 | ALDH1A1 (0.73) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL37221912 | 0.87 | ALDH1A1 (0.73) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16756047 | 0.87 | ALDH1A1 (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16756019 | 0.85 | ALDH1A1 (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5392425 | 0.84 | ALDH1A1 (0.55) | KDM4EGAAALDH1A1MAPTHPGD | |
| SCHEMBL3220939 | 0.84 | MEN1 (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL22346709 | 0.83 | KMT2A (0.54) | KDM4EGAAALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-9061994-B1 | Materials and methods useful to induce vacuolization, cell death, or a combination thereof | THE UNIVERSITY OF TOLEDO (US) | 2015-06-23 | — | — | US | disclosed |
| US-20150152049-A1 | Materials And Methods Useful To Induce Vacuolization, Cell Death, Or A Combination Thereof | THE UNIVERSITY OF TOLEDO (US) | 2015-06-04 | — | — | US | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152049-A1 | Materials And Methods Useful To Induce Vacuolization, Cell Death, Or A Combination Thereof | BECN1, BAD, BAX | TUBB4A 131/4885TUBB 161/4885TUBA3C 339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.