Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | ATP4A | P20648 | 2/20 | 0.35 |
| ▸ | ATP4B | P51164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10110055 | 0.77 | ALDH1A1 (1.00) | ALDH1A1RAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL23162497 | 0.73 | ALDH1A1 (0.66) | ALDH1A1RAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL5357915 | 0.73 | ALDH1A1 (0.70) | ALDH1A1RAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL5357917 | 0.73 | ALDH1A1 (0.70) | ALDH1A1RAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL23162498 | 0.73 | ALDH1A1 (0.66) | ALDH1A1RAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL23207060 | 0.73 | ALDH1A1 (0.66) | ALDH1A1RAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL3112087 | 0.70 | ALDH1A1 (0.73) | ALDH1A1RAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL3112082 | 0.70 | ALDH1A1 (0.73) | ALDH1A1RAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL3017848 | 0.69 | ALDH1A1 (0.64) | ALDH1A1RAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL3017850 | 0.69 | ALDH1A1 (0.64) | ALDH1A1RAB9ASMN1; SMN2NPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |