Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557097 | 0.86 | TDP1 (0.47) | PTGDR2ERN1ALDH1A1MAPTTDP1 | |
| SCHEMBL14785422 | 0.85 | HTR2B (0.48) | PTGDR2ERN1ALDH1A1MAPTTDP1 | |
| SCHEMBL14785171 | 0.84 | PTGDR2 (0.44) | PTGDR2ERN1ALDH1A1MAPTTDP1 | |
| SCHEMBL2556401 | 0.83 | PTGDR2 (0.70) | PTGDR2ERN1ALDH1A1MAPTTDP1 | |
| SCHEMBL14785358 | 0.82 | PTGDR2 (0.43) | PTGDR2ERN1ALDH1A1MAPTTDP1 | |
| SCHEMBL14785283 | 0.82 | PTGDR2 (0.43) | PTGDR2ERN1ALDH1A1MAPTTDP1 | |
| SCHEMBL2556226 | 0.82 | PTGDR2 (0.49) | PTGDR2ERN1ALDH1A1MAPTKDM4E | |
| SCHEMBL1714052 | 0.81 | PTGDR2 (0.68) | PTGDR2ALDH1A1MAPTTDP1KDM4E | |
| SCHEMBL2559901 | 0.80 | ALDH1A1 (0.56) | PTGDR2ERN1ALDH1A1MAPTTDP1 | |
| SCHEMBL15332229 | 0.79 | KDM4E (0.58) | PTGDR2ERN1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |