SCHEMBL15330449

SCHEMBL15330449

CCC(Oc1c(C=O)cccc1OC)C(N)=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.50
ERN1 O75460 2/20 0.47
TLR2 O60603 1/20 0.47
TLR1 Q15399 1/20 0.47
TLR6 Q9Y2C9 1/20 0.47
NFE2L2 Q16236 3/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
KDM4E B2RXH2 3/20 0.40
POLB P06746 2/20 0.40
LMNA P02545 2/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
CYP1A1 P04798 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
APOBEC3A P31941 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15330863 0.88 KMT2A (0.41) SRCERN1TLR2TLR1TLR6
SCHEMBL28792232 0.88 SRC (0.51) SRCERN1TLR2TLR1TLR6
SCHEMBL28792280 0.86 SRC (0.49) SRCERN1TLR2TLR1TLR6
SCHEMBL15330946 0.83 CA1 (0.38) SRCERN1TLR2TLR1TLR6
SCHEMBL15333363 0.82 SRC (0.54) SRCERN1TLR2TLR1TLR6
SCHEMBL2559432 0.82 PTGDR2 (0.46) SRCERN1TLR2TLR1TLR6
SCHEMBL6200062 0.78 KMT2A (0.53) CA1CA2KDM4EPOLBLMNA
SCHEMBL2558195 0.77 ALDH1A1 (0.51) KDM4EHPGDTSHRCYP1A2MAPT
SCHEMBL6599199 0.76 SRC (0.50) SRCERN1TLR2TLR1TLR6
SCHEMBL2560577 0.76 SRC (0.50) SRCERN1TLR2TLR1TLR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed