SCHEMBL15330741

SCHEMBL15330741

Cc1cc(C=O)c(O)c([C@H](N)CCCO)c1

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 3/20 0.50
SRC P12931 2/20 0.33
GRK6 P43250 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15331606 1.00 ERN1 (0.50) ERN1SRCGRK6
SCHEMBL15330981 0.96 ERN1 (0.49) ERN1SRCGRK6
SCHEMBL15330776 0.96 ERN1 (0.49) ERN1SRCGRK6
SCHEMBL2561255 0.91 ERN1 (0.53) ERN1SRCGRK6
SCHEMBL15332204 0.91 ERN1 (0.53) ERN1SRCGRK6
SCHEMBL15333065 0.85 ERN1 (0.53) ERN1SRCGRK6
SCHEMBL15331771 0.85 ERN1 (0.53) ERN1SRCGRK6
SCHEMBL15329806 0.85 ERN1 (0.56) ERN1SRCGRK6
SCHEMBL2556348 0.85 ERN1 (0.56) ERN1SRCGRK6
SCHEMBL29952548 0.85 ERN1 (0.46) ERN1SRCGRK6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed