Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 13/20 | 0.56 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | GRK6 | P43250 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15329806 | 1.00 | ERN1 (0.56) | ERN1SRCGRK6LMNAMAPT | |
| SCHEMBL2561255 | 0.88 | ERN1 (0.53) | ERN1SRCGRK6LMNAMAPT | |
| SCHEMBL15332204 | 0.88 | ERN1 (0.53) | ERN1SRCGRK6LMNAMAPT | |
| SCHEMBL15331019 | 0.87 | ERN1 (0.56) | ERN1SRCGRK6LMNA | |
| SCHEMBL15332113 | 0.87 | ERN1 (0.56) | ERN1SRCGRK6LMNAMAPT | |
| SCHEMBL15329877 | 0.87 | ERN1 (0.56) | ERN1SRCGRK6LMNAMAPT | |
| SCHEMBL15330741 | 0.85 | ERN1 (0.50) | ERN1SRCGRK6 | |
| SCHEMBL15331606 | 0.85 | ERN1 (0.50) | ERN1SRCGRK6 | |
| SCHEMBL15331771 | 0.84 | ERN1 (0.53) | ERN1SRCGRK6ALDH1A1 | |
| SCHEMBL15333065 | 0.84 | ERN1 (0.53) | ERN1SRCGRK6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |