Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | STK17A | Q9UEE5 | 8/20 | 0.46 |
| ▸ | GRM5 | P41594 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | STK17B | O94768 | 4/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15332393 | 0.82 | RAB9A (0.47) | HDAC3HDAC1HDAC2HDAC6STK17A | |
| SCHEMBL23094602 | 0.81 | HDAC6 (0.53) | HDAC6STK17AKDRSYK | |
| SCHEMBL15332714 | 0.80 | HDAC3 (0.59) | HDAC3HDAC1HDAC2HDAC6GRM5 | |
| SCHEMBL15331048 | 0.79 | NPC1 (0.49) | HDAC3HDAC1HDAC2HDAC6HSD17B10 | |
| SCHEMBL15332616 | 0.78 | HDAC3 (0.58) | HDAC3HDAC1HDAC2HDAC6GRM5 | |
| SCHEMBL4503013 | 0.77 | GRM5 (0.47) | HSD17B10STK17AGRM5POLBSTK17B | |
| SCHEMBL15332185 | 0.77 | SYK (0.56) | POLBKDRSYK | |
| SCHEMBL14801200 | 0.76 | HDAC3 (0.53) | HDAC3HDAC1HDAC2HDAC6STK17A | |
| SCHEMBL22191302 | 0.76 | HDAC3 (0.56) | HDAC3HDAC1HDAC2HDAC6STK17A | |
| SCHEMBL3651535 | 0.75 | RAB9A (0.44) | HDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |