Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 15/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.35 |
| ▸ | FAP | Q12884 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15028066 | 0.86 | DPP4 (0.51) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL15712090 | 0.81 | DPP4 (0.41) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL15334874 | 0.79 | DPP4 (0.33) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL13285559 | 0.78 | DPP4 (0.59) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL15386522 | 0.78 | DPP4 (0.59) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL13259718 | 0.78 | DPP4 (0.59) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL15712089 | 0.78 | METAP2 (0.33) | DPP4METAP2EPHX1 | |
| SCHEMBL15028132 | 0.74 | DPP4 (0.38) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL15334872 | 0.74 | DPP4 (0.44) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL13259713 | 0.73 | DPP4 (0.40) | DPP4DPP8DPP7DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8563533-B2 | Soft protease inhibitors and pro-soft forms thereof | TRUSTEES OF TUFTS COLLEGE (US) | 2013-10-22 | — | — | US | disclosed |