SCHEMBL15340306

SCHEMBL15340306

CCCC1CCC(c2ccc(-c3ccc(C4CCC(CC)CC4)cc3)c(F)c2C(F)F)CO1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.33
CYP2C9 P11712 1/20 0.31
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
MEN1 O00255 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15340053 0.87 PDE9A (0.30)
SCHEMBL9927716 0.85 ALOX5 (0.38) ALOX5CYP2C9ALDH1A1LMNAMAPT
SCHEMBL9927780 0.84 CYP2C9 (0.39) ALOX5CYP2C9ALDH1A1LMNAMAPT
SCHEMBL15343749 0.83 NPC1 (0.36)
SCHEMBL15340375 0.81 FASN (0.35) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL9927738 0.81 ALOX5 (0.39) ALOX5
SCHEMBL9927781 0.80 CYP2C9 (0.34) ALOX5CYP2C9ALDH1A1LMNAMAPT
SCHEMBL15340057 0.80 FFAR4 (0.31)
SCHEMBL15340047 0.80 OPRL1 (0.36) ALOX5CYP2C9ALDH1A1LMNAMAPT
SCHEMBL13066740 0.80 CYP2C9 (0.33) CYP2C9ALDH1A1LMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9102871-B2 Liquid crystal compound showing negative dielectric anisotropy, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-08-11 US disclosed
US-9102871-B2 Liquid crystal compound showing negative dielectric anisotropy, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-08-11 US disclosed
US-20130277610-A1 LIQUID CRYSTAL COMPOUND SHOWING NEGATIVE DIELECTRIC ANISOTROPY, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-10-24 US disclosed
US-20130277610-A1 LIQUID CRYSTAL COMPOUND SHOWING NEGATIVE DIELECTRIC ANISOTROPY, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-10-24 US disclosed