⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25130206 | 0.80 | — | — | |
| SCHEMBL15131909 | 0.77 | MAPK1 (0.38) | — | |
| SCHEMBL12972309 | 0.74 | — | — | |
| SCHEMBL7682659 | 0.74 | TSHR (0.41) | — | |
| SCHEMBL431399 | 0.74 | — | — | |
| SCHEMBL6686581 | 0.74 | — | — | |
| SCHEMBL11131624 | 0.74 | — | — | |
| SCHEMBL18646288 | 0.73 | — | — | |
| SCHEMBL3629853 | 0.72 | — | — | |
| SCHEMBL23637744 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754607-B | Oxadiazole compound and application thereof | 沈阳化工大学 | 2023-09-05 | — | — | CN | disclosed |
| CN-113754607-A | Oxadiazole compound and application thereof | 沈阳化工大学 | 2021-12-07 | — | — | CN | disclosed |
| EP-3275861-A1 | TETRACYCLINE COMPOUNDS | Tetraphase Pharmaceuticals, Inc. (US) | 2018-01-31 | — | — | EP | disclosed |
| US-20170334841-A1 | TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS, INC. | 2017-11-23 | — | — | US | disclosed |
| EP-2470500-B1 | TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS INC (US) | 2017-10-04 | — | — | EP | disclosed |
| US-9624166-B2 | Tetracycline compounds | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2017-04-18 | — | — | US | disclosed |
| EP-2707371-B1 | NEW HEXAHYDROPYRROLOIMIDAZOLONE COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2016-04-20 | — | — | EP | disclosed |
| US-8497288-B2 | Hexahydropyrroloimidazolone compounds | HOFFMANN-LA ROCHE INC. (US) | 2013-07-30 | — | — | US | disclosed |
| US-20120289549-A1 | NEW HEXAHYDROPYRROLOIMIDAZOLONE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-11-15 | — | — | US | disclosed |
| US-20120208788-A1 | Tetracycline Compounds | TETRAPHASE PHARMACEUTICALS, INC. | 2012-08-16 | — | — | US | disclosed |
| EP-2470500-A2 | TETRACYCLINE COMPOUNDS | Tetraphase Pharmaceuticals, Inc. (US) | 2012-07-04 | — | — | EP | disclosed |
| WO-2011025982-A2 | TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2011-03-03 | — | — | WO | disclosed |
| US-4846873-A | 1-carboalkoxyalkyl-3-alkoxy-4-(2'-carboxyphenyl)-azet-2-ones as plant growth regulators and selective herbicides | CHEVRON RESEARCH COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| WO-1987007270-A1 | 1-CARBOALKOXYALKYL-3-ALKOXY-4-(2'-CARBOXYPHENYL)-AZET-2-ONES AS PLANT GROWTH REGULATORS AND SELECTIVE HERBICIDES | CHEVRON RESEARCH COMPANY (US) | 1987-12-03 | — | — | WO | disclosed |
| US-4602012-A | Cephalosporin antibiotics | GLAXO GROUP LIMITED (GB) | 1986-07-22 | — | — | US | disclosed |
| US-4260624-A | Fungicidal 2-substituted-3-oxa-3a lambda4,4-dithia-6-chloro-1,5-diazapentalene | CHEVRON RESEARCH COMPANY (US) | 1981-04-07 | — | — | US | disclosed |